I must sample their handles for videogame character names.
The problem isnt that this still is casually available. Drugs have been casually available since forever.
The problem is that pushing drug usage to the fringes makes it less safe for people who haven’t done their homework. Ironically the exact opposite of that you claimed.
Personally, I'd rather have a proper doctor prescribe me said medicine than take it myself.
Is that actually the common thing to do amongst recreational psychadelics users (i.e. is there research backing this up)?
And how do these folks "understand the substance(s)"? We (humanity) know very little about how the brain works comparatively as far as I'm aware, and psychadelics research is further relatively lacking due to regulatory and funding constraints. Most resources I hear of just seem to be compilations of anecdata, frequently muddled with subjective remarks.
Bit like asking where all the beer drinkers are! People who are into psychedelics come from all walks of life and we're everywhere :) Start talking about fringe stuff with people and eventually you'll stumble upon others.
I agree this is important, which is why psychedelics should be legalized so there is at least some sort of control instead of the current approach where 14 year olds can easier get their hands on it.
https://www.folklore.org/Joining_Apple_Computer.html
Still very sad that HyperCard got sidelined and that even its successor, Livecode abandoned the idea of being available to everyone --- though it looks as if folks are still working that:
Teens will always get their hands on things so it’s up to parents to teach kids how to be safe around drugs and alcohol, but I know I personally will be really trying to communicate to my kids that they need to wait until they’re 18 to really start exploring all this stuff. I know they will before that, but as long as it’s a little experimentation here and there and not regular use I’ll consider it a success.
Once you’re past 18 or so, it needs to be all about education and general availability for most substances. Safe usage and community protections (such as not driving while intoxicated) should be the #1 goal.
We were able to clarify it and we're both being decent sports about the topic, but you can imagine how well this might go over in less careful and open minded situations. Or even desperate ones.
I'm curious in what demographic/location context you're in to say that. As a teen I wasn't aware of anyone in my social circles experimenting with drugs and would estimate usage to be <10% and from very particular kinds of people.
Furthermore, I've had mixed experiences with health professionals. It took me 10 years across multiple clinics and states to get diagnosed with gout that I've had since at least my late teens. Laughed out of multiple doctor's offices because I'm a "healthy young male" even though each day and night was filled with excruciating pain and drastically reduced mobility. "Full test panels" that specifically did not test my uric acid, because no healthy young male has gout.
No mention of gout ever to me, of course. I had to self diagnose as the disease progressed due to lack of treatment. Got my diagnosis confirmed by a physician's assistant, because both doctors at that clinic were on vacation at the same time for like the third time that quarter. He ordered a uric acid test, and was surprised that I'd never been offered one.
Both doctors had literally laughed me out of the office over the previous months. But I was persistent and it turns out the physician's assistant there was both more thorough and more knowledgeable than either doctor, helping me finally begin a path to treatment. I was damn near about to kill myself from a decade of extraordinary pain. From my discussions with older, typical gout sufferers, my case is extraordinarily bad and most of them only experience mild pain.
It's equally as silly to place 100% trust in doctors as it is to place 0% trust in them.
I personally have never taken DMT though from everything I've read and heard on podcasts it's not something to be taken lightly. I think having a sort of "DMT Clinic" that you can go to would be the best middle ground of allowing the public access to these substances while also ensuring that there is a trained professional there to guide you through the process.
Saying "trained professional" in this context feels wired because this stuff has been underground for so long but I think it's starting to bubble up into the mainstream enough that we need to start bringing all that "into the light". Lets have training programs that teach people how to administer this stuff properly, how to deal with the negative side effects, etc.
One of the things that while I find understandable is ridiculous is the fact that Bill had to use a pseudonym in the community. I feel like if were at the point where you have C-suite types at Apple taking this stuff, it's time to think about making it available to the broader public.
The medical community is concerned with physical health, mental health, ect.
The Psychedelic community is more like a religion; it is "vast" and there is a lot of "shared knowledge" if you go looking. The thing is, western medicine's purpose really isn't to do the kind of thing that psychedelics are for.
It's probably better not to conflate the two communities, because they use drugs for very different purposes.
A different way to say it: Don't confuse the pharmacy and the liquor store.
Compounding the issue is the eye-rolling hypocrisy that in the so-called "Land of the Free", a healthcare system controlled by the gatekeepers of big pharma and for-profit companies gets a blind pass... but putting certain plants (that you can grow yourself) into your own body is considered a serious felony...?
There's at least a sliver of daylight here that mean YMMV (which I'm sure you and I would agree on) - but if you lack the freedom to choose anyways, then it doesn't matter. And the people who decide for you are clearly part of a system that is compromised by regulatory capture, political polarization, and the insatiable greed of American healthcare.
Understanding the risks of buying potentially adulterated or counterfeit products is another thing entirely, which would be helped greatly by increased commodification and legalization.
If I go buy some psychedelic, chances are it is diluted or laced, so I would have to know how to test that what they sell me is what I asked for.
If they are safe to be around and are able to hold a job or have children, then there's societal benefits gained. One could consider the treatment costs as investments.
If that person was untreated and they did something unpleasant or bad in public, or ended up in prison, that also has a cost to society though it might be more complex to quantify.
It's entirely natural, easy to do, has no side effects, costs next to nothing, and can even be "fun". As usual, the media will not talk about this discovery, as it is too much of a game-changer for our current systems.
[0] https://neurosciencenews.com/psilocybin-longevity-aging-2942...
The only way in the US is to have a powerful lobby that can fight to ensure broad waivers stand up in court, like the NRA: you can buy a gun and literally shoot yourself in the foot.
But if transaction, money, service, profession are all removed, then under a co-op / non profit this might work. Of course, those structures are also vulnerable to well-funded legal opponents.
Some European countries do provide a framework for this but it's more from a public health perspective and to eliminate the raison-d'être of criminal drug organizations.
I was getting ads for MindMed's clinical trials of their LSD analogue a few months back and was considering signing up for it, as I'm totally down with more scientific research on these compounds. However, the idea that a corporation with a patent on an analogue that is lobbying to make it so their version is the one that is approved is kinda the worst. We already have LSD, it's cheap and it's amazing, yet here we are marching down the road of some patented version being the one that's approved for use. I get that these companies want to fund research, but this isn't the way.
We often attract certain types of people, and have a wealth of experience with that type.
We probably all take this as obvious knowledge. But only when I uncomfortably enter a group of people unlike me -- and feel totally alienated not just by their norms and assumptions, but their misunderstandings of my own -- only then do I truly confront the implications in a visceral, non-academic sense :)
I wouldn't say a word if it weren't nth article about psychedelics that appears on HN frontpage. I was quiet the last n-1 times.
If you google psilocybin right now, you can see articles that state how it "slows ageing" and "cures depression". There probably is some truth to it, but only in very specific sense and specific circumstances. Most people will NOT benefit from taking the drug (as with any drug).
So it hurts my soul when I see words like "legalize" being thrown in this context. We know very very little about effect of such drugs. And the goal should not be to legalize, but rather to expand our knowledge on how it works, and create safe medicine that actually helps people.
Rant is over now. Thank you.
motorcycles...? in... my eyes?
What wizardry is this? First "computers in my brain", now this. I'll have the singularity that you're smoking pls :)
EDIT: was at first genuinely confused, and then tickled by my own misunderstanding
https://lfpress.com/news/local-news/european-cough-medicine-...
That seems like exactly when we should legalize it. The default is legal, and without definite knowledge of serious harm, that should be the status.
The burden of proof should be on the people who want it to be legal, and by your comment, their case seems pretty weak.
What surprises me the most is that we have accepted sugar, alcohol, cigarettes and a ton of mass manufactured food which are harming us. I am struggling with high blood glucose for 12 years. Yet, the substance which I can grow in my* own backyard and may actually not be as harmful is just brainwashed out of my limits.
edits: you to me
If we assume that the effect is the same for all types of cells, it follows that the life is extended by 50% (when keeping "all other factors" constant, as usual).
An article just came out showing that psilocybin extends life in aged mice, so that’s why you’re seeing it a lot. Yet we have no idea what causes this lifespan increase. Is it a result of “hallucination” experience itself , a purely chemical effect, or something in between? (aka will a ‘bad trip’ give the same effect on lifespan?)
> Most people will NOT benefit from taking the drug (as with any drug)
Now you’re just making things up.
Timothy Leary's Mind Mirror (1985) (usc.edu)
https://scalar.usc.edu/works/timothy-leary-software/index
https://news.ycombinator.com/item?id=32578683
https://www.youtube.com/watch?v=9oabRxvjf9k
I extracted all the text and data from the Apple ][ floppy disk:
https://news.ycombinator.com/item?id=37486524
https://donhopkins.com/home/mind-mirror.txt
https://github.com/SimHacker/lloooomm/tree/main/00-Character...
One of the commenters of your post says "If we legalize it we can better research it". Allow me to be rude -- this is BS. If we follow this logic we should legalize pretty much everything!
I think it is polite to be rude to such dangerous thoughts. Downvote me as you see fit.
Bringing it into the light under thoughtful consideration and openly discussing and encouraging harm prevention is the only way to make this safe. Everyone should have the right to to exploring this if they want to, and there should be plenty of open discussion, research, and education. I really appreciate the open-source approach here, the spirit of this movement feels like the right thing for humanity.
I guess we could do something like:
<normal coverage> - <adjustment for risky behavior> + <adjustment for pro-social outcomes>
But I think we will have trouble puzzling out the last term!(From the photo caption) "Bill ... with his iphone prototype"
Nope. That's a Sony Magic Link, built by Bill (and others, myself included) during his time at General Magic. I feel General Magic is another one of Bill's endeavors that isn't widely understood or appreciated.
It took me years to be diagnosed with PTSD, a problem I knew I had. Because I am not a vet, I had to go through every other diagnosis first -- schizo, bipolar, borderline -- each with a new set of pills to take. Some of the shrinks who diagnosed me wouldn't do anything but open my file, make some remarks, and fill out a prescription, with nary any eye contact.
Finally got a very expensive doctor who wasn't under the thumb of insurance companies. Her first question, upon hearing my issues, was "how is your sleep?" "I don't, really" was my reply. Screened me for PTSD and I clocked 76/80 pts. She set me up with the proper therapy, and within a year, I was screening at 30/80 pts. All it took was asking me one question that wasn't loaded towards the doctors favorite diagnosis & prescription.
If you don't know what's wrong with you, then a doctor is absolutely the way to go. But if you already have a diagnosis, you can go spend time researching it, the doctor isn't going to do that.
Citing Sam Harris:
“Ingesting a powerful dose of a psychedelic drug is like strapping oneself to a rocket without a guidance system. One might wind up somewhere worth going, and, depending on the compound and one’s “set and setting,” certain trajectories are more likely than others. But however methodically one prepares for the voyage, one can still be hurled into states of mind so painful and confusing as to be indistinguishable from psychosis.”
“This is not to say that everyone should take psychedelics. As I will make clear below, these drugs pose certain dangers. Undoubtedly, some people cannot afford to give the anchor of sanity even the slightest tug.”
Example that just came across my news feed: "psilocin, a byproduct of consuming psilocybin, the active ingredient in psychedelic mushrooms, extended the cellular lifespan of human skin and lung cells by more than 50%."
https://neurosciencenews.com/psilocybin-longevity-aging-2942...
Of course you have to find such a shop (hint: try Canada), and it's still a lot of hassle for something that should be perfectly legal, and is, in many places.
No surprise that, in keeping with the hacker spirit, Bill wanted to democratize information that is otherwise accessible only to "high" priests.
Governments should not be in the business of banning things unless there's a clear and present danger. Citizens should have the autonomy to do risky things if they want to.
I myself have had bad / hell like experiences a small percentage of the time, despite literal hundreds of good experiences prior.
Becoming a father many years ago significantly altered my trip experience.
Dosage also plays a strong role..
These things are generally less toxic than alcohol and it is criminal to punish someone for having them or using them.. But they are also extremely powerful, and despite potential amazing experiences, do carry risks.
And they are definitely not for everyone.
However you said that your not knowledgeable and I guess that you doesn't have access to a milligrams scale, so your better to stay away and learn the theory first. A lot of psilocybin analog (alpha-MethylTryptamine was one of my favorite and it's still available) from Thikal are still legal in Canada so that book is a good place to start learning.
The resistance is real, systematic, and rational (from the perspective of maintaining current power arrangements). Not a joke.
I strongly disagree. Your circles might be different, but in my experience, wanting to do your homework makes it less accessible, because it tends to put you at odds with the people who are otherwise eager to grant you access. They want people with a certain mindset and an up-front faith in the process. They want people who aren't careful about ingesting psychoactive substances, are eager to put their mental health in the hands of some guy they barely know, and are going to blame their own baggage or spiritual shortcomings if it doesn't go well.
These drugs, and many others, are already pretty accessible if you are willing to take that heedless approach.
In contrast, the approach described in the article is expressly tailored for people who want to be careful and do their homework. It's for people who have access to the drug and implicitly already have access to cruder ways of using it, but who want to put in extra effort for a more controlled experience.
Acetaminophen is the one that still mysterious, there are credible theories but they don't explain everything the substance does. The latest one I know of is that one : https://www.pnas.org/doi/10.1073/pnas.2413811122
Well, Ayahuasca (with DMT as the active ingredient) retreats seem more and more common and are for some reasons tolerated more and more in europe. Technically it is illegal, but I can still book them online.
But I won't, as I don't trust the competence of the average new age "shaman".
For example, someone might have insights about the interconnectedness of all life and wants to transition to regenerative agriculture or communal land use, but face zoning laws that enforce individual property ownership. Or someone might experience ego dissolution and wants to create more egalitarian workplace structures, but runs into rigid corporate hierarchies.
https://www.oregon.gov/oha/ph/preventionwellness/pages/psilo...
"A client may only access psilocybin at a licensed service center during an administration session in the presence of a trained, licensed facilitator."
The point is that western civilization values rationality, order, and progress in a self-justifying way. The values that our culture provides to us form a feedback cycle of myth and virtue. Every argument that assumes this basis, reinforces its truth.
"Order is obviously preferable to chaos", is one of many subjective perspectives. Why should it hold more truth than "Plurality of perspectives are obviously preferable to the fragility of one perspective for the sake of objectivity"? The apparatuses of the state[1] all rely on the same cultural myth and promote it in a way that crowds out all possible alternatives. Thus the myth of necessary order has become synonymous with reality.
Like all deeply rooted cultural myths, this is something that's going to appear obviously true which coincidentally serves as a way of shielding it from honest critique. If there's one thing that I've learned, it's that questioning foundational myths feels like a cultural violation. René Girard’s theory holds; when a community is anxious or unstable, it lashes out most viciously at people who somehow threaten its central, but unspoken, truths or anxieties. The greater the received response that a cultural axiom obviously true; the more certain I am that it reflects a core cultural myth than any semblance of reality.
1. See Louis Althusser, Ideology and Ideological State Apparatuses, 1970.
So... this clinic was not entirely unlike what you're proposing w/ DMT.
FWIW, the results were incredible. I was effectively "cured." But unfortunately my insurance changed, and it became no longer covered, and I couldn't afford the $2000 every six weeks for the treatment anymore. And it's not super convenient to take two hours off from work to go to the trip-sitter's to get the treatments.
I hope that they figure out what it is in psychadelics that make them effective at treating stuff like depression and PTSD and make it more accessible because it seems like there's so much potential there.
(Also: fuck Elon Musk for making Ketamine a punchline)
"why, there's no magazine called 'Weird' is there?" [0]
Motorcycle cops are an obvious subset of people who ride motorcycles. It isn’t an extension at all to include them in your logic.
ATVs might be more of an extension. But, I bet if we wanted to we could find all sorts of jobs that are more dangerous than motorcycle riding.
(Edit: just to be specific, you say we have to draw the line somewhere. Well, then where?)
> substantially longer duration of the former
When time stops until the end of this universe gives way to the beginning of this universe and the snake eats it's tail, "longer" doesn't hold much meaning...What I had my friend made. Bought some root, had to use naptha to separate it in a fridge then put it (powder) on top of something flammable and smoke it like weed.
Further thoughts:
On a side note/comparison, weed for me it's like. Day to day you're driven by a known process/system. You have to get to work at 9 AM, go to this, then that. Smoking weed you stop and are in the moment, suddenly focused on how vibrant this red shrub is that you normally ignore. I don't smoke weed anymore because it makes me super paranoid like afraid cops are going to arrest me or I can't interact with people as I already have social anxiety. The other thing is it would enforce my delusions thinking some idea was great/fixate on some design (I was trying to use it to come up with ideas to make money).
DMT is like losing steady state/reality, solid things start to move. The colors were not solid for me, it's like when you push your eyes (while closed) and you see flashes of light. This was a long time ago I did it so might not be remembering as well, it was intense though and brief.
I have not done acid or shrooms as I have bad repressed childhood memories and I don't want to get stuck in that for hours.
Did K one time, I just sat on a couch throughout a party doing nothing/sipping on a cup of water.
K2/Salvia that stuff was whack, I felt like I was sinking into a couch when I smoked it in a shed with a buddy and I felt dumb like I couldn't talk correctly.
C and Addy, amazing. I mean if you could operate life like that all the time you'd probably die just because you'd do crazy things like do a jump that you normally wouldn't just because of the overconfidence. But yeah the ability to sit down/cram 12 hrs of work and pass a test, amazing or nail every note on a guitar. The weight loss is great but I found my p would shrink so much it was crazy. At one point started to defecate blood (was just a fissure) so yeah that was a problem. I would use A for times when I couldn't get sleep and would just do these overnighters at a data-entry job.
Also did M before (fake addy) and yeah, that's great for drinking, you can just pound beers/liquor and not feel it. The bad thing is the come downs, you are drained of happiness, can't do anything and it is hard to recover. A way to recover is to jerk off a lot. But yeah I don't do that anymore just because the sadness is crazy.
Years back, my friend’s parents asked me to stage an intervention for him after they found out he regularly took LSD. He was 19 at the time.
(If you do this, make sure you inject the upper-outer quadrant. The closer to your midline you go, the further the risk of you hitting a nerve.)
If you're very experienced and want to do it for novelty's sake, go for it; I'd warn you, but anyone considering this should know what they're likely in for.
Nearly immediately after injection, I became so filled with vibrating, psychedelic energy I thought my soul was going to be ripped from my body. I had to clutch the edge of the sink, trying not to vomit while staring at the exploding fractals swirling in the metallic reflection.
It only lasts about 2 hours. I'd not particularly rate the experience as "good".
In the time since, my views have changed dramatically on these substances, and I'd like to try more of them. However, my personal moral compass prevents me from using substances outside of a legally permissible setting, at least at present - and that's something I'm fine with.
Ultimately, the taboo side of things is something the individual has to grapple with on their own. I can only commiserate with your frustrations, not help overcome them unfortunately. My only other advice would be to use any substance only to amplify good vibes, never to cope with bad ones.
If all you do is chase a lost feeling, you're missing out on what's in front of you now.
One of my first times after, in my experience, I literally went to hell. I was convinced I was on the outskirts, all the people at the party around me were demons, I was about to be tortured forever, and I was never going to see my son again and he was going to grow up without me..
I convinced myself I was in that position because I had wrecked and killed someone, and my punishment was forever replaying the experiencing of a life where I would grow up to have a son, only to have him ripped away from me, reminded of what I did, and then tortured for some nearly eternal amount of time....
Any conversations people had with me at the time, I heard the words they were saying but completely twisted the meaning of the words to fit whatever crazy narrative was going on in my head.
This has happened 4 or 5 times. Despite being familiar with the experience, in my mind it just reinforces that I am in a "loop" at the time, about to be tortured again..
It's happened with LSD, Mushrooms, and surprisingly even ketamine. *edit it also happened during an intense changa experience with a shaman in Tijuana, which was my most intense experience with anything to date..
You'd think I would not take this stuff anymore =p I have at least slowed down considerably...
I'd say it is worth looking at redrawing that based on the maximum effect achieved. Drugs would be at the top of this list, followed by motor vehicle use and unhealthy foods. There is probably not enough justification to go beyond the 3.
Individual insight doesn't map to institutional action. Systems can't integrate experiences they can't measure or systematize.
I do think that there are some truths to government desire for narrative management, too. It is unwise to be a hugger in a knife fight, and you don't want the populace to get high, see God, and deteriorate national security.
All in all though, it all boils down to life being complicated. The resistance isn't adversarial - it's structural. Which makes it both less intentionally evil and harder to overcome.
I guess I’ve been beating around the bush, but my point is that targeting drugs specifically for this sort of thing would seem kind of, I dunno, puritanical to me (as someone who doesn’t partake). I’d rather just insure everybody and hope they don’t hurt themselves, just out of their own self interest.
As an atheist with no supernatural beliefs (that I know of), I wonder if a trip on LSD for me would just be boring, or if these supernatural things become real during a trip even if you don't truly believe in them.
https://en.wikipedia.org/wiki/5-MeO-DMT#Effects
https://qualiacomputing.com/2020/07/01/5-meo-dmt-vs-nn-dmt-t...
Regardless of your beliefs, whatever your experience, I highly doubt you would find it "boring".
I can't even imagine that really, it would take a very boring person.
I've heard a lot of acid stories, but never "I was just kind of bored"
In the SF bay area – & plenty of other regions around the world – the criminal enforcement against hallucinogens is, de facto, a very low priority as long as you're not flagrantly endangering or inconveniencing others.
My other drug of choice is adrenaline from driving fast my car currently tops out just under 160mph and I'd go even faster if I could but maybe thankfully I can't. Fear is funny too, I don't fear this but I fear talking to people ha.
I'm trying to stop this because the tickets part, I only screw around on highways when I'm alone and day time, I don't do swimming/cutting people off but yeah.
The speed thing is easy get an old ZR1 it can go 200 but going in a straight line can be boring. It's the acceleration. Recently been watching this guy drive an Elise down roads in Switzerland that's pretty fun and not that fast. I know you can track too but idk.
"Big Reality" was either terrified of everyone becoming drooling monkeys, or people seeing behind the curtain of society, depending on who you ask.
Timothy Leary might've drawn a parallel on the psychological impact of computers (I have no idea on the exact quote or it's context), which is enormous, but computers are just not psychedelic.
Put differently, while an idea being established and self-justifying doesn't necessarily mean it's exclusive in these traits and should be bolted in, sure, an idea being fringe also doesn't necessarily mean it's unjustly fringe at all, or that it's being unfairly discriminated against. To claim so without evidence is little more than conspiratorial thinking and self-victimization.
It further sounds really quite self-serving to paint e.g. me as some misguided sheep part of some malicious cabal for this. It's a little more than just a variation on the all too common ill faith ways of argumentation; mixing in the semantic specifics of psychedelic experiences, name dropping people, movements, and quotes, and deferring to a "specific" culture's particularities serves at most as a distraction from this.
Seems like it.
I did it one time and there was no vomitting and feeling great the day after.
But that maybe was, because the plant that was used was apparently not so strong. So yes, it is from natural plants, that can have very different concentrations. I suppose this is what the documentary means with life threatening poisening? Getting a plant that had a unusual high concentration?
But I never heard of those horror stories from people who do it regulary. (Vomitting is quite normal, though) Otherwise I have limited knowledge in that area, but I do know with mushrooms for example, you can use different ones of the same species to mix them to average out concentration differences. I assume the same can be done with Ayuahasca. But like I said, I would not recommend the commercial retreats anyway.
(I did it when I was invited into a ceremony in a remote place by people who were not frauds)
the normal dose is 5-10mg, but LD50 in sheep is about 100mg, it might be as low as 30mg in humans.
It absolutely should not be legal, at least to anyone. Perhaps require training in dealing with drugs with a low therapeutic index
Also the vast majority of people are done purging within a few hours...not "days"
(Source: work at retreat center and have drank hundreds of times)
It's actually quite the opposite. True-believers overwhelmingly disseminate cultural myths. It's the police officer who believes they can positively affect the enforcement of order, educators who base values in the rational order of the mind. It's journalists and pundits who frame news as a tension between order (good, stable) and chaos (bad, dangerous). Where deviance is newsworthy primarily as a threat to order. See news cycles on crime, protests, economic instability, all in terms of order must be "restored."
Look at the modern workplace, for instance, obsessed with order, predictability, and process (think: KPIs, best practices, Six Sigma). And corporate culture manuals and onboarding training reinforcing norms of punctuality, control, and rational planning.
It's present in engineers, scientists, architects, IT managers - professions often celebrated as the apex of rational, orderly progress and as solutions to messy[chaotic] problems. Even here, it's easy to gain karma dunking on the liberal arts, all because science is assumed more value because it more closely aligns with necessary order.
None of these roles form a secret cabal. Still, they enforce and perpetuate the cultural value system whose results are judged on the basis of order.
No one is saying that chaos is good or order is bad. It’s that the binary itself is a function of our cultural mythmaking. When psychedelics make that myth visible, the reaction isn't to consider the critique, but to defend the myth as "reality."
Respectfully, this is nonsense. Ask anyone who lived in Libya under Gaddafi and then in the years since, or who lived under any other despotic regime and compare it to the chaos that ensued when the despot is removed.
Civilization’s association with order is not random (or a function of “cultural myth making”); chaos _sucks_.
That seems quite unlikely given that there are many 30mg dose trip reports, going as far back as TiHKAL.
From personal experience, this is de-facto true regardless of what anyone thinks the law says.
If your bubble has people in it who have access to psychedelics, then great. If one's people doesn't have that, "just talk to people" is profoundly unhelpful. That's a very odd and specific conversation to bring up within some circles.
For 5-meo I generally do 6-8mg prepared as above. That seems subjectively close to 15-20mg vaped (powder in a glass pipe not in a “juice” vape).
But either of those are definitely a commitment to the ride, lol. I do like the mixed jaguar vape cartridges for micro dosing though (like Bill prepares them in the article). Very easy to control your dosage that way with the ability to start slow and add more with additional puffs.
I would describe 5-meo as a trip that gives you an immediate understanding of how life and the universe “works” at a very fundamental level. Your perception changes from analytical type thinking to all of a sudden just knowing how everything fits together and how you can control reality around you. A bit like pulling the curtain back and seeing the source code of realty but then also intuitively knowing how to manipulate and rewrite it and seeing the effects of that in real time.
I wish I could explain it better.
In terms of ROA between vaping and IM get the same type of knowing but from a different perspective. Injected feels like your personal programming code gets rewritten and you have a reality shift to having administrator privileges while vaped feels like the person that wrote the code is a co-pilot in your head explaining how the code is written and how it executes to present as reality to you.
There’s definitely a lot of overlap between each roa type though.
What I describe above is also my experience after dozens of trips with 5-Meo. The first few were definitely more confusing and at times overwhelming as the perspective shift can be severe. Once you get experienced though it’s a fun way to cruise around in “reality”
> By the time they’re in 12th grade, 46.6% of teens have tried illicit drugs.
How does it work? Is the half-life of it shorter when administered IV?
1–5 mg/kg IV
1–2 mg/kg SC
85 mg/kg O
In mice:
75–115 mg/kg IP
48 mg/kg IV
113 mg/kg SC
278 mg/kg O
They were administering over 30mg to humans in trials. (Metzner (2013); Shulgin and Shulgin (1997); Ott (2001); Davis et al. (2018); Uthaug et al. (2020a))
Sheep are susceptible to toxicity from certain tryptamine alkaloids because of their physiology.
These alkaloids, especially those that are N,N-dimethylated, can trigger neurological symptoms in sheep, such as convulsions, spasticity, and gait issues. The alkaloids are suspected to affect the brain and spinal cord by interacting with serotonin receptors.
5-MeO-DMT is an N,N-dimethylated compound. Its full chemical name is 5-methoxy-N,N-dimethyltryptamine. That indicates the presence of two methyl groups attached to the nitrogen atom of the tryptamine backbone.
Stay safe, everyone!
> However, my personal moral compass prevents me from using substances outside of a legally permissible setting, at least at present - and that's something I'm fine with.
What on Earth do laws have to do with morals?
You’re opening yourself up to blackmail by hundreds of different parties.
It is blatantly irresponsible to host such communities on Discord. Possession and use are federal felonies.
with this stupidity, maybe you should try eating list of 20 deadly plants and see how it goes?
"ownership" means "edible/nose-able"... maybe you should try eating your car?