Type 2 diabetes: New treatment eliminates insulin for 86% of patients

Not sarcasm: I'm sure it would be frustrating to see so much scientific and commercial effort going into treating TIID pharmacologically when you believe the solution is trivial. But you could also consider all of these developments as evidence that the prescription of "just eat healthy" isn't broadly useful.

100% agree, it's a modern cultural problem. We look for drug and technology solutions because "doing the right thing" is hard.

> But you could also consider all of these developments as evidence that the prescription of "just eat healthy" isn't broadly useful.

As programmers, we usually prefer to remove code to fix a bug than adding patches on top of buggy code. Let's not pretend that the same logic does not apply here.

That's clearly double unhealthy behavior and will bring unintended consequences. Which might be better than the current predicament but still let's not pretend this is not a "monkeypatch".

GLP-1 drugs don’t make you burn fat, they make you eat healthy (or healthier, at least). That’s why they’re so amazingly effective and the reason why is even more amazing - they hack your reward subsystem.

When you say "it's a modern cultural problem", do you mean, as most people appear to mean, "This is not a social problem worth solving, these people deserve it for their moral failings, and their death is a useful example for the rest of us"?

Most people don't actually say it out loud, but this is all directly implied by the "personal responsibility" retort that is wildly popular among people who don't actually suffer from a given malady, in response to attempts to address it collectively.

GLP-1 drugs seem to increase resting heart rate. I suspect that also increases total daily energy expenditure, although I don't know that we have reliable data on that yet.

That can happen, but is not universal. My resting heart rate has been dropping (probably in lock step with my weight), it has not risen one bit since I started taking tirzepatide. And my heart rate variability has been trending up, not down.

Why do you suspect it changes energy expenditure?

Friendly fwiw: Your parent clearly does not think it is a "modern cultural problem":

  > "when _you_ believe the solution is trivial" (emphasis mine)

They were trying to start a polite dialogue with you by displaying that they could see things from your purview. Probably with the hope of building common-ground that would, in turn, invite you to maybe see the other side:

  > "But you could also consider..."

Perhaps reconsider their olive branch?

not OP, but I agree it is modern cultural problem and a personal responsibility problem.

However, I dont agree with your supposition following from that.

I think that obesity is a symptom of a cultural problem worth solving, not an individual moral failing, and there are better ways to learn than death.

There are lots of things in our culture that result in physical and mental sickness. It is good to treat the symptoms, but we should also pay attention to the cause.

Culture operates both at the individual and collective level. One can not exist without the other. One can not change without changing the other. Personal beliefs and actions shape collective culture, and culture shapes personal beliefs.

We have government policy that reshaped American agriculture 70 years ago to lower the cost curve for food. That was accomplished by industrialization of food production. That drives Americans to eat the way they do.

Travel to Italy or France and the difference is shocking — both in terms of the look of the people and the quality of the food.

There are also very relevant cultural differences between the French and Americans. It is not just the food on the shelves, or price, but healthy attitudes and behavior around eating and life in general.

The average American is 50% richer than the average French, and have access to everything they need to eat like one if they choose.

In fact, much of the difference is the French choosing not to eat - both in terms of frequency and quantity.

Healthy food attitudes can absolutely be learned and taught. If you see a 200lb 10 year old, the difference between them and their classmates isn't the contents of the supermarket. Its what is going on at home, the actions of their parents, and what they are learning.

I say this not to blame or pass judgement, but to demonstrate that induvial behavior and actions matter.

Biologically, obesity could be seen as a win.

It is the natural consequence of the human body's strategy for finding enough sustenance to drive that big brain over an evolutionary timeline that was mostly dominated by scarcity.

We like to call it a disease because we want to live longer. But all of the consequences happen after most humans have procreated, so there is no evolutionary pressure[0] to change it.

[0] Yes, I understand evolution isn't quite that simple

Obesity reduces fertility for both sexes. This is one of the factors behind declining birth rates.