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Bill Atkinson's psychedelic user interface

(patternproject.substack.com)
455 points cainxinth | 3 comments | | HN request time: 0.831s | source
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_fat_santa ◴[] No.44531760[source]
We need to push to make this stuff legal. I wouldn't go so far as to say lets sell it OTC vape pens at gas stations but a middle ground where you can go to a doctor to have this treatment performed.

I personally have never taken DMT though from everything I've read and heard on podcasts it's not something to be taken lightly. I think having a sort of "DMT Clinic" that you can go to would be the best middle ground of allowing the public access to these substances while also ensuring that there is a trained professional there to guide you through the process.

Saying "trained professional" in this context feels wired because this stuff has been underground for so long but I think it's starting to bubble up into the mainstream enough that we need to start bringing all that "into the light". Lets have training programs that teach people how to administer this stuff properly, how to deal with the negative side effects, etc.

One of the things that while I find understandable is ridiculous is the fact that Bill had to use a pseudonym in the community. I feel like if were at the point where you have C-suite types at Apple taking this stuff, it's time to think about making it available to the broader public.

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mosburger ◴[] No.44535108[source]
Last year I underwent treatments for my treatment-resistant major depression using Ketamine. It was a clinical setting, where you'd get wired up to blood pressure, pulse-ox, and other monitors while you were monitored by an RN via video camera. This was IV Ketamine, so not the inhalants that are available now. According to the clinic, the inhalants (which they also offered) are also generally less effective than IV, and the IV was safer in my case because I have other medical conditions where being able to "shut it off" was a good thing - you can turn an IV off, but once you inhale, you're on your own.

So... this clinic was not entirely unlike what you're proposing w/ DMT.

FWIW, the results were incredible. I was effectively "cured." But unfortunately my insurance changed, and it became no longer covered, and I couldn't afford the $2000 every six weeks for the treatment anymore. And it's not super convenient to take two hours off from work to go to the trip-sitter's to get the treatments.

I hope that they figure out what it is in psychadelics that make them effective at treating stuff like depression and PTSD and make it more accessible because it seems like there's so much potential there.

(Also: fuck Elon Musk for making Ketamine a punchline)

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notpushkin ◴[] No.44540208[source]
> being able to "shut it off" was a good thing - you can turn an IV off, but once you inhale, you're on your own

How does it work? Is the half-life of it shorter when administered IV?

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1. gavinray ◴[] No.44541332[source]
I had a Ketamine infusion done at a clinic in Miami.

It was $600 (discounted) for the first infusion.

You go through a pre-evaluation with the doctor, where they determine a dosage for you based on prior experience and bodyweight.

My clinic also offered to co-administer IV benzos to prevent panic attacks or negative experiences, which was a HUGE plus for me.

During the experience you're given a button, which you can press to call them and have the drip turned off or turned down.

If it wasn't so expensive or covered by my insurance, I would've certainly repeated it.

Highly recommend.

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2. notpushkin ◴[] No.44541491[source]
Very interesting, thanks for sharing! I’ve read that you can get your hands on a solution for Ketamine injections (or, if you have pure Ketamine, just prepare one yourself). Most go for intra-muscular injections instead (~70% bioavailability compared to IV, still great compared to ~10% when snorted). The reason they give is, when administered IV it wears off way too quickly – I guess drip solves this one!

This is, of course, way more risky and pretty much illegal I guess, but it should probably be cheaper?

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3. gavinray ◴[] No.44541644[source]
It'll be significantly cheaper, and assuming you purchase the Ketamine from a reputable source/vendor and use a test kit on it, the risk is comparatively "minimal".

Not necessarily "condoning" the behavior, so much as sharing harm-minimization info here:

For safe/sterile injection, you need three things, all cheaply + easily available on the internet.

1) Bacteriostatic water - https://www.amazon.com/bacteriostatic-water/s?k=bacteriostat...

2) Sealed, sterile vials for preparation of the solution - https://www.amazon.com/Sterile-Vial/s?k=Sterile+Vial

3) Insulin syringes. 29g 0.5" work well. https://www.amazon.com/s?k=29g+1cc+1%2F2+inch+insulin+syring...

See my comment in this thread about IM administration of 4-AcO-DMT for more info:

https://news.ycombinator.com/item?id=44535690