←back to thread

Weight-loss drug found to shrink muscle in mice, human cells

(www.ualberta.ca)
263 points Eumenes | 2 comments | 20 Nov 24 23:53 UTC | HN request time: 3.513s | source
Show context
diath ◴[21 Nov 24 05:15 UTC] No.42201353[source]▶
The problem with appetite suppression drugs is that they simply make you not feel hungry, but do nothing to fix your lack of discipline and self-control, I'm sure most people who lose weight on these drugs, and then come off, will just go back to their bad habits.
replies(4): >>42201405 #>>42201431 #>>42201669 #>>42201938 #
echoangle ◴[21 Nov 24 05:26 UTC] No.42201405[source]▶
So why not just stay on the drugs?
replies(3): >>42201423 #>>42201436 #>>42202081 #
bluSCALE4 ◴[21 Nov 24 05:33 UTC] No.42201436[source]▶
Most kill you. If I didn't misread articles on ozempic, they can cause digestive problems where food rots in your stomach. Bad depression was another side effect which blows my mind since you'd think looking better would make you feel great. And these were the minor things.
replies(3): >>42201450 #>>42201474 #>>42201523 #
cthalupa ◴[21 Nov 24 05:37 UTC] No.42201450[source]▶
> digestive problems where food rots in your stomach

I assume you mean gastroparesis - this is an extremely rare side effect

> Bad depression

Again, pretty rare side effect.

If you think these are the minor things I'm confused as to what you think the major side effects are.

replies(1): >>42202270 #
1. Elinvynia ◴[21 Nov 24 08:31 UTC] No.42202270[source]▶
Gastroparesis is literally the method of action of GLP1 agonists. It slows gastric motility. Gastroparesis is literally slowed motility of the stomach (where 20% of food stays in your stomach after 4 hours). It doesn't matter why, that is the literal diagnostic criteria, ergo it literally causes gastroparesis.
replies(1): >>42203467 #
2. cthalupa ◴[21 Nov 24 12:02 UTC] No.42203467[source]▶
Your position does not match that of medical researchers.

https://jamanetwork.com/journals/jama/fullarticle/2810542

https://pmc.ncbi.nlm.nih.gov/articles/PMC10874596/

https://pubmed.ncbi.nlm.nih.gov/38443105/

Or more plainly worded

https://www.healthline.com/health-news/ozempic-wegovy-stomac...

Some people develop permanent gastroparesis.