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206 points pseudolus | 3 comments | | HN request time: 0s | source
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robertakarobin ◴[] No.46008748[source]
I was very young when my mom started Prozac but do remember how angry and sad she was before compared to after.

Years later there was a time when me and my sister noticed our mom was acting a bit strange -- more snappish and irritable than usual, and she even started dressing differently. Then at dinner she announced proudly that she had been off Prozac for a month. My sister and I looked at each other and at the same time went, "Ohhhh!" Mom was shocked that we'd noticed such a difference in her behavior and started taking the medication again.

I've been on the exact same dose as her for 15 years, and my 7-year-old son just started half that dose.

If I have a good day it's impossible to day whether that's due to Prozac. But since starting Prozac I have been much more likely to have good days than bad. So, since Prozac is cheap and I don't seem to suffer any side effects, I plan to keep taking it in perpetuity.

What I tell my kids is that getting depressed, feeling sad, feeling hopeless -- those are all normal feelings that everyone has from time to time. Pills can't or shouldn't keep you from feeling depressed if you have something to be depressed about. Pills are for people who feel depressed but don't have something to be depressed about -- they have food, shelter, friends, opportunities to contribute and be productive, nothing traumatic has happened, but they feel hopeless anyway -- and that's called Depression, which is different from "being depressed."

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techietim ◴[] No.46008941[source]
> my 7-year-old son just started half that dose

This is horrifying.

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kstrauser ◴[] No.46008980[source]
Why? If a kid has diabetes, would it be horrifying to treat it? Why would it be different for a neurochemistry issue that makes the same kid tired and sad all the time?
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jacobgkau ◴[] No.46009004[source]
Because the problem's not a "neurochemistry issue" (that theory's been debunked and the "chemicals" in play have never been known), and the solution is "no better than placebo."
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dekhn ◴[] No.46009233[source]
Please share your qualifications for making a statement like this- do you work in biology? Are you knowledgeable about the underlying biology here, and the limitations of medical publications?
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1. tremon ◴[] No.46009830[source]
I hope you do realize that this comment thread is linked to an article that includes the words "Prozac no better than placebo" in its headline?
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2. dekhn ◴[] No.46009926[source]
Yes, I do. I don't consider articles in the regular press to be even remotely worth looking at due to their high rate of inaccuracy. Here's the paper that the article refers to: https://www.jclinepi.com/article/S0895-4356%2825%2900349-X/f...
3. malfist ◴[] No.46010746[source]
These types of studies are published all the time and can easily be dismissed. Antidepressants are _only_ for major depression. Not mild or moderate. These studies that find no significance compared to a placebo are always tried in patients with all types of depression. Not just major.

It's so common it's a trope. "Antidepressants don't work" says the scientists testing antidepressants on things they're not supposed to work on.

Studies repeated with just major depression all conclude antidepressants are better than a placebo.

Click through the article to the study and you'll find they did not limit their study to must major