AFAIK some neurodivergent brains deal with amphetamines differently and the baseline levels of chemical affected by amphetamines is different.
Wear and tear might be a thing, i don't know, but the analogy of putting NO2 in their car feels a bit off.
It'd be more like finally putting premium unleaded in your car after years of "back of the lorry" pseudo-unleaded.
That said, it completely destroyed my appetite. I picked up ciggies, too. It made me crave nicotine and caffeine. I started pulling all-nighters because I was so productive (or, so into whatever game I was playing.) I got cold sweats often and had some weird uh sexual health side effects. Develeoped a tolerance to 5-10mg very quickly, so went up to 15-20mg, which also felt weakened after a month or so.
So, wasn't lolng before I could tell this was not healthy. Felt like I was in overdrive mode - super mentally active, and productive, but running my body into the ground. I would never do it long-term.