Aldous Huxley predicts Adderall and champions alternative therapies

amphetamines feel a lot like people putting NO2 on their cars, or overclocking their computers. You might just fine in the end, but the likelihood of wear & tear catching up to you increases. It should be treated just like any other medicine, don't use it unless you really have to, and expect adverse effect (known or unknown).

Isn't the whole point of amphetamine based treatement for ADHD to correct(or beneficially alter, depending on your point of view) an non-standard brain chemistry?

AFAIK some neurodivergent brains deal with amphetamines differently and the baseline levels of chemical affected by amphetamines is different.

Wear and tear might be a thing, i don't know, but the analogy of putting NO2 in their car feels a bit off.

It'd be more like finally putting premium unleaded in your car after years of "back of the lorry" pseudo-unleaded.

I believe parent commenter was referring to recreational use, i.e., use by people without such diagnoses who want a "performance boost". I heard about that sort of thing being popular when I was in college — people would take Adderall to cram for an exam or to study late into the night.

You're right that, for people with ADHD and related disorders, stimulant medication sort of just adjusts their baselines so they can pay attention like a "normal" person.

> You're right that, for people with ADHD and related disorders, stimulant medication sort of just adjusts their baselines so they can pay attention like a "normal" person.

I have ADHD and take metylphenidate(I've tried many kinds of stimulants as well) -- and the NO2 analogy is an imperfect but better analogy than saying stimulants simply adjusts the baseline of people with ADHD to function like "normal" persons.

I feel there is a narrow window of dosage and time where it might feel that way -- i.e. stimulants at the onset might calm you down, reduce anxiety, but all stimulants are very broad hammers.

For me it feels like it's impossible to re-create chemically exactly the neurotypical focus that I've seen in other colleagues.

Like spending 5-6 hours of continous work where you drill down just enough, get back on track, don't get distracted, don't get too anxious, don't get hyperfocused AND do that consistently, day after day after day.

My non-chemical modes are either hyper focus for 2 weeks on a problem, immerse myself but then completely lose interest, most of the time without showing much for it OR procastinate it a long way, get extremely anxious and work really hard on the problem.

With stimulants it's a bit like: - dosed just right:it evaporates anxiety, stressful situations feel easy to deal with, BUT there's always increased heart rate, grinding teeth and some tension at the end of the day - some stimulants make mundane things wildly interesting (on isopropylphenidate I spent a few hours playing with a PLSQL debugger because I thought it was really cool), but no sense of "GO, GO, GO, do it". - some make things seem urgent enough and help stay on track -- like the metylphenidate I'm prescribed. - some make going into a flow-like state easy and fun (like methamphetamine and phenmetrazine). - some are pure energy and urgency -- like modafinil.

All of the stimulants have the potential to give me euphoria, all of them temporarily increase libido I still have to be mindful of not focusing on the wrong thing, the "normal" feeling is very fleeting, it's very easy to get hyper on stimulants, all of them feel like wear & tear at the end of the day, some more than others.