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215 points XzetaU8 | 1 comments | | HN request time: 0s | source
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ACCount37 ◴[] No.45081066[source]
Aging isn't even recognized as a disease yet, and it well should be.

Very little research currently goes into attacking aging directly - as opposed to handling things that are in no small part downstream from aging, such as heart disease. A big reason for poor "longevity gains" is lack of trying.

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seanmcdirmid ◴[] No.45081119[source]
That’s kind of naive. Plenty of people definitely “try”, billionaires would love to live a few hundred more years. We know how aging occurs, there is degradation in DNA, telomeres shorten, and a bunch of other things. The main problem is that biological life simply can’t undergo overhauls like machines do, and we will probably just solve aging by creating successor beings that can.
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ACCount37 ◴[] No.45081246[source]
Just compare the effort and the investment that goes into fighting aging with what goes into fighting cancer.

You can't rely on billionaires to fix everything for you. The kind of research effort that would be required to make meaningful progress against aging would likely demand hundreds of billions, spent across decades. Few billionaires have the pockets deep enough to bankroll something like this, or the long term vision.

Getting aging recognized as a disease and a therapeutic target, and getting the initial effort on the scale of Human Genome Project would be a good starting point though.

If there was understanding that a drug "against aging" is desirable by the healthcare systems and can get approved, Big Pharma would have a reason to try - as opposed to developing drugs for other things and hopefully stumbling on something that makes progress against aging by an accident.

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imtringued ◴[] No.45081308{3}[source]
Bill Gates has enough money for effective longevity research. Longevity research isn't even particularly expensive.

The actual problem is that you would have to do selective breeding and genetic modification of humans the same way we do it with plants and animals. It is primarily an ethical problem.

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1. ACCount37 ◴[] No.45081592{4}[source]
Not necessarily. We already have drugs that can hit "genetic disease" targets in adults, and we can modify adult genomes to a minor degree.

Sure, it would be nigh impossible to do something like cram "genetic resistance to cancer" into a grown adult with current day tech, but there are other surfaces to attack in longevity.