Beginning 1 September, we will need to geoblock Mississippi IPs

Clueless human, but what stops a company from ignoring these laws from certain states? How is this enforceable if a company doesn't have any infrastructure within that state?

Now I am curious as well. Are there…extradition treaties between states?

The treaty in question is the Constitution. All states must grant extradition to any other state.

It would be pretty crazy if you could kill someone in Arizona and then just walk over the border to California and not be able to be prosecuted…

You mean the Zone Of Death?

https://en.wikipedia.org/wiki/Zone_of_Death_(Yellowstone)

"The Zone of Death is the 50-square-mile (130 km2) area in the Idaho section of Yellowstone National Park in which, as a result of the Vicinage Clause in the Constitution of the United States, a person may be able to theoretically avoid conviction for any major crime, up to and including murder"

That's a separate thing -- it's not about being in a different state from where the crime was committed, it's about (supposedly) it being procedurally impossible to give you the jury trial you have to have, because literally no one lives in the relevant district.