It's active intranasally and well as buccally/sublingually.
Effects-wise, it feels roughly identical to DMT but with a longer duration.
I made this mistake exactly once, with 4-AcO-DMT.
That was the last time I ever did such a thing.
(If you do this, make sure you inject the upper-outer quadrant. The closer to your midline you go, the further the risk of you hitting a nerve.)
If you're very experienced and want to do it for novelty's sake, go for it; I'd warn you, but anyone considering this should know what they're likely in for.
Nearly immediately after injection, I became so filled with vibrating, psychedelic energy I thought my soul was going to be ripped from my body. I had to clutch the edge of the sink, trying not to vomit while staring at the exploding fractals swirling in the metallic reflection.
It only lasts about 2 hours. I'd not particularly rate the experience as "good".