How would topical application work, and what kind of homeostasis effect, from ingestion.
If you are low on vitamin c in your diet, sure. If not, you may not get much benefit from having more.
IMO, everybody should take at least 2g daily in a couple of doses, particularly smokers.
Most people can get enough vitamin C each day from food or drink. 3/4 cup of orange juice daily is enough. https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-h...
Taking vitamin C orally decreases muscle mitochondrial biogenesis and harms the health benefits of training, like increased insulin resistance. (well established from multiple studies, easy to google).
There was huge antioxidant craze in late 90's and 00's when taking antioxidant supplements like C was considered the right thing to do. Now we know that just taking more antioxidants does not directly help with oxidization tress, because it messes up metabolism and can even increase it.
Today he would reject orthomolecular medicine, because he was an intelligent man and believed evidence.