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134 points gnabgib | 2 comments | | HN request time: 0.399s | source
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ggm ◴[] No.44450388[source]
In cell cultures. So nothing about topical, or digestive pathways. Just, expose cells to vitamin c rich medium.

How would topical application work, and what kind of homeostasis effect, from ingestion.

If you are low on vitamin c in your diet, sure. If not, you may not get much benefit from having more.

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majkinetor ◴[] No.44452463[source]
Everybody is low on C in diet. It's thermolabile, and there is glucose competition for GLUT transporters.

IMO, everybody should take at least 2g daily in a couple of doses, particularly smokers.

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1. jb1991 ◴[] No.44460877[source]
> IMO, everybody should take at least 2g daily in a couple of doses

I strongly caution against this kind of blanket recommendation. For most people, taking such a high dose without medical guidance is unwise. Unless a healthcare professional has specifically advised it, this level of supplementation goes well beyond established guidelines.

There is substantial research highlighting potential risks, including kidney damage, associated with high-dose vitamin C intake (as referenced elsewhere in this thread).

Anyone considering this should thoroughly research the risks and consult a qualified medical professional before proceeding.

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2. ◴[] No.44460926[source]