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1165 points jbredeche | 2 comments | | HN request time: 0.516s | source
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MrZander ◴[] No.43998447[source]
> To accomplish that feat, the treatment is wrapped in fatty lipid molecules to protect it from degradation in the blood on its way to the liver, where the edit will be made. Inside the lipids are instructions that command the cells to produce an enzyme that edits the gene. They also carry a molecular GPS — CRISPR — which was altered to crawl along a person’s DNA until it finds the exact DNA letter that needs to be changed.

That is one of the most incredible things I have ever read.

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poyu ◴[] No.43998602[source]
Made it sound like it's a computer, is it Turing complete?
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buzzy_hacker ◴[] No.43998991[source]
Made me think of

    It was only in college, when I read Douglas Hofstadter’s Gödel, Escher, Bach, that I came to understand cells as recursively self-modifying programs. The language alone was evocative. It suggested that the embryo—DNA making RNA, RNA making protein, protein regulating the transcription of DNA into RNA—was like a small Lisp program, with macros begetting macros begetting macros, the source code containing within it all of the instructions required for life on Earth. Could anything more interesting be imagined?

    Someone should have said this to me:

    > Imagine a flashy spaceship lands in your backyard. The door opens and you are invited to investigate everything to see what you can learn. The technology is clearly millions of years beyond what we can make.
    >
    > This is biology.
   
    –Bert Hubert, “Our Amazing Immune System”
from https://jsomers.net/i-should-have-loved-biology/
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1. duskwuff ◴[] No.43999620[source]
>> Imagine a flashy spaceship

I misread this as "fleshy" for a moment, and the quote almost works better that way.

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2. floam ◴[] No.44011631[source]
Me too. It did. Huh.