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76 points docmechanic | 1 comments | 29 Mar 25 13:39 UTC | HN request time: 0s | source

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yarnover ◴[02 Apr 25 07:35 UTC] No.43554452[source]▶

It has happened in plants over and over again.

echelon ◴[02 Apr 25 11:37 UTC] No.43555635[source]▶

Gene dose increases in plants lead to bigger vegetables and fruiting bodies. We've taken advantage of this during domestication of several species.

Gene dose increases in animals lead to total dysfunction and death in embryonic development.

dekhn ◴[02 Apr 25 17:28 UTC] No.43559104[source]▶

dose is such a weird term for "copies"

replies(1): >>43559445 #

flobosg ◴[02 Apr 25 18:02 UTC] No.43559445[source]▶

It’s quite… historical.

replies(1): >>43560448 #

echelon ◴[02 Apr 25 19:18 UTC] No.43560448{4}[source]▶

Historical-sounding, maybe? It's still used in the literature:

1. flobosg ◴[02 Apr 25 23:06 UTC] No.43562818{5}[source]▶

A term can be still used in literature for historical reasons. Both concepts are not mutually exclusive.

Scientists uncover key mechanism in evolution: Whole-genome duplication drives