Once GrapheneOS is installed, no further interaction with Google is required. You can happily and easily use a main profile without play services/Gapps (and Graphene allows you to block 'network' at the socket layer if you do need to use apps).
You could then have a 'work' profile or use private space which is isolated from your main profile that uses play services/app store but it is absolutely not required.
It _is_ a learning curve for sure, but I do not feel Google is going out of its way like Microsoft is here to make it burdensome. (In fact, Google is quite welcoming to OEM unlocking unlike some other phone manufacturers)
My brother is stunned that I'm still using such an old phone (8 year old Moto). Unfortunately, no recent model Moto phones can run Lineage. My next phone will probably be a Pixel with Graphene or Lineage.