Much more influential 16-bit CPUs from that era include the PDP-11's CPU, the Data General Nova's CPU, the Xerox Alto's CPU, and arguably even the 8086 and 8088. The chronology seems to go as follows:
- 01965: IBM 1130
- 01966: HP 2116A, the first model of the HP 2100 series
- 01969: Nova
- 01970: PDP-11
- 01971: IBM System/7
- 01973: Alto (not shipped. NEVER shipped)
- 01973: TI-990 (the 990/3, according to https://cozx.com/dpitts/ti990.html)
- 01974: HP 3000
- 01974: PACE (which was from National Semiconductor, not National Instruments)
- 01975: CP1600
- 01976: TMS9900 (what the TI-99/4A used)
- 01976: Tandem (first Tandem/16 shipped to Citibank)
- 01978: 8086
- 01979: 8088
- 01981: TI-99/4A
Since there were plenty of 6-bit, 8-bit, 12-bit, 32-bit, 36-bit, 60-bit, and 64-bit CPUs in the 01950s, you'd think there would be some 16-bit CPUs then too, but I can't think of any. I'd even forgotten about the HP 2100 until I went looking just now.