Some Americans were left behind in Afghanistan, and thirteen Marines were killed there due to the incompetent execution of the withdrawal. Other Americans were taken hostage by Hamas with next to no serious effort to recover them. Many were fired from their jobs or discharged from the military if they refused to take an experimental vaccine. Others who took the vaccine suffered myocarditis and other vaccine injuries. Many people have overdosed on fentanyl or fallen victim to gangs like Tren de Aragua that simply walked across the open southern border. Tens of thousands of US construction jobs were destroyed by the cancellation of the Keystone XL pipeline. I can keep going but I think I've made my point.
And if you're not just counting US citizens, there's a war in Ukraine that's killed over a million people and another war in Gaza, the latter of which was precipitated by the bloodiest mass killing of Jews since the Holocaust.