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Weight-loss drug found to shrink muscle in mice, human cells

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372 points Eumenes | 1 comments | 20 Nov 24 23:53 UTC | HN request time: 0.207s | source
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kbos87 ◴[21 Nov 24 02:14 UTC] No.42200375[source]▶
There are a lot of people here citing loss of muscle mass as a side effect of GLP-1s, when the reality is that weight loss almost always comes with muscle loss.

For me, that hasn't even been the case. I'm down 40lbs on a relatively low dose of Semaglutide and my muscle mass has moderately increased over the last 6 months. The hysteria over this is totally unfounded.

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1. ChiperSoft ◴[22 Nov 24 06:58 UTC] No.42211708[source]▶
Meanwhile I’ve been on ozempic since 2021 and have lost significant muscle mass despite gaining 50 pounds (the drug helps with my diabetes but does nothing to my appetite).