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Weight-loss drug found to shrink muscle in mice, human cells

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372 points Eumenes | 1 comments | 20 Nov 24 23:53 UTC | HN request time: 0.207s | source
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siliconc0w ◴[21 Nov 24 01:52 UTC] No.42200253[source]▶
It's pretty clear that GLP-1 should be prescribed with protein powder. When your appetite is crushed you don't go for the chicken breast, you go for what is immediately appetizing (usually carbs+fats like pizza or fries). IMO this and a lack of resistance training (which should also be prescribed) probably makes up a large % of the muscle loss on these drugs. The problem is that the FDA only looks at dumb measures like weight lost, not body fat % when approving these drugs.
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1. wan23 ◴[21 Nov 24 22:36 UTC] No.42209408[source]▶
Going to add to the chorus here. One of the reasons these things are so successful is that it kind of kills the crave factor of eating. You don't get that feeling where you feel like you want to keep eating something addictive like pizza or fries just because it's there. It's why the packaged food companies are freaking out - all their work to engineer snacks where they can "bet you can't eat just one" is defeated by these, at least for now.