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Weight-loss drug found to shrink muscle in mice, human cells

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263 points Eumenes | 1 comments | 20 Nov 24 23:53 UTC | HN request time: 0.222s | source
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kbos87 ◴[21 Nov 24 02:14 UTC] No.42200375[source]▶
There are a lot of people here citing loss of muscle mass as a side effect of GLP-1s, when the reality is that weight loss almost always comes with muscle loss.

For me, that hasn't even been the case. I'm down 40lbs on a relatively low dose of Semaglutide and my muscle mass has moderately increased over the last 6 months. The hysteria over this is totally unfounded.

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1. Etheryte ◴[21 Nov 24 08:55 UTC] No.42202377[source]▶
Your sample size is one. Imagine how a study saying this would get picked apart if their sample size was one. You have no idea whether you're in the middle of the normal distribution bell curve or at one of the extreme ends.