←back to thread

Weight-loss drug found to shrink muscle in mice, human cells

(www.ualberta.ca)
234 points Eumenes | 1 comments | 20 Nov 24 23:53 UTC | HN request time: 0s | source
Show context
siliconc0w ◴[21 Nov 24 01:52 UTC] No.42200253[source]▶
It's pretty clear that GLP-1 should be prescribed with protein powder. When your appetite is crushed you don't go for the chicken breast, you go for what is immediately appetizing (usually carbs+fats like pizza or fries). IMO this and a lack of resistance training (which should also be prescribed) probably makes up a large % of the muscle loss on these drugs. The problem is that the FDA only looks at dumb measures like weight lost, not body fat % when approving these drugs.
replies(4): >>42200377 #>>42201167 #>>42201253 #>>42201499 #
1. phil21 ◴[21 Nov 24 05:50 UTC] No.42201499[source]▶
Tirzepatide let me stay away from the immediately appetizing junk food and almost exclusively eat a clean diet focused on protein.

My experience matches at least a dozen folks in my personal bubble. It’s sort of the point of the drug or it wouldn’t work very well.

Totally agreed on resistance training. The one thing I would change would have been starting that in a serious manner as soon I started the drug vs. waiting. Prescribing it is silly though - if that worked we wouldn’t need the drugs to begin with.