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Weight-loss drug found to shrink muscle in mice, human cells

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234 points Eumenes | 2 comments | 20 Nov 24 23:53 UTC | HN request time: 0s | source
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jyscao ◴[21 Nov 24 00:46 UTC] No.42199859[source]▶
When Ozempic started making the rounds in the news with glowing reviews, my instincts told me there likely was some long term negative effective that wasn't immediately apparent yet.

If something sounds good too good to be true, it usually is.

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1. m463 ◴[21 Nov 24 05:29 UTC] No.42201420[source]▶
On the other hand, being overweight takes years off your life:

"Specifically, we found that BMIs from 40 to 44 were associated with 6.5 years of life lost, but this increased to 8.9 for BMIs from 45 to 49, 9.8 for BMIs from 50 to 54, and 13.7 for BMIs from 55 to 59."

I think for some people the roi is measurable and reasonable.

https://irp.nih.gov/blog/post/2020/01/extreme-obesity-shaves...

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2. watwut ◴[21 Nov 24 08:33 UTC] No.42202279[source]▶
Being obese takes years off your life. Being slightly overweight is associated with best longevity.

BMIs from 40 to 44 is massively obese, not overweight.