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Weight-loss drug found to shrink muscle in mice, human cells

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234 points Eumenes | 1 comments | 20 Nov 24 23:53 UTC | HN request time: 0.351s | source
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siliconc0w ◴[21 Nov 24 01:52 UTC] No.42200253[source]▶
It's pretty clear that GLP-1 should be prescribed with protein powder. When your appetite is crushed you don't go for the chicken breast, you go for what is immediately appetizing (usually carbs+fats like pizza or fries). IMO this and a lack of resistance training (which should also be prescribed) probably makes up a large % of the muscle loss on these drugs. The problem is that the FDA only looks at dumb measures like weight lost, not body fat % when approving these drugs.
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1. technofiend ◴[21 Nov 24 04:55 UTC] No.42201253[source]▶
That may be your experience, it wasn't mine. I eat very healthy on Ozempic but yeah of the 60 lbs lost so far some of it is noticeably muscle because I don't exercise enough. The next 60 lbs of fat lost will hopefully be me swapping fat for muscle from weight lifting and swimming.