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201 points andsoitis | 4 comments | | HN request time: 0.88s | source
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aucisson_masque ◴[] No.41853580[source]
> Can we overcome ageing?

75% American are overweight..

Just let it sink a second, they speak about how many baby born after 2000 will reach 100 years old, how we are reaching the absolute limit of human survival.

75% overweight... Everyone know fat people don't live long. I bet all the studies done in the 90's that predicted we would easily be able to reach 100 years old didn't take that into account.

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scarby2 ◴[] No.41853689[source]
I'm thinking that ozempic and zepbound will have something to say about this. When ozempic becomes available as a generic (2032) it's going to be available for $10 a dose and a huge amount of people will be taking it.
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Muromec ◴[] No.41853798[source]
Wait, doing amphetamines for weight loss is cool again and has no drawbacks of it's own?
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llm_trw ◴[] No.41853996[source]
Welcome to the 80s part 2. Hope you enjoy the ride.
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llamaimperative ◴[] No.41854467[source]
Ozempic et al are nothing like amphetamines. They definitely have side-effects but we have far, far more evidence that the benefits are outweighed than we did for stimulants in the 80s.
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1. llm_trw ◴[] No.41855511[source]
Every decade or two I hear this about some wonder drug only for them to turn out just as bad as what they were replacing. The opioid epidemic being the latest one.
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2. ywvcbk ◴[] No.41856917[source]
Do you pay more attention to those and ignore the actual success stories?

The opioids thing is hardly comparable. Everybody clearly knew the risks (for the past 100+ years) and chose to ignore them. This is an almost entirely new type of drugs.

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3. llm_trw ◴[] No.41857544[source]
Do you pay attention to the people who win at Russian roulette more than those who lose?

OxyContin was marketed to be the safe alternative to all opioids that came before it, impossible to become addicted to and extremely difficult to overdose from. This was a lie.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140023/

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4. ywvcbk ◴[] No.41859272{3}[source]
> Do you pay attention to the people who win at Russian roulette more than those who lose?

Well.. no since you cant really win anything. With pharmaceuticals on the other I hand I think 1 Oxycontin/etc. like “situation” would be a reasonable price to pay for let’s say 4 major successes.

You were talking about decades. Surely you noticed the advancements in treating cancer, HIV and a multitude of other conditions since the 90s?

> This was a lie.

Sure. But it’s on the same level as saying that filtered cigarettes don’t cause cancer. If a doctor actually believes that he’s just too dumb to be a doctor… (although I assume most safety claims were relative to other opioids and not in absolute terms?)

Are there any signs that the situation with Semaglutides is that similar? Yes they are new and not well understood drugs (well not really but sort of..) and it’s not inconceivable that their longterm cost might end up outweighing the benefits but I don’t really see any signs of an actual conspiracy yet.