Using an external monitor with OS X, you're often stuck with those in-between sizes if you don't either have hawkeyes or enjoy seeing super-crisp 1080p resolution taking up half of your desk, which is a waste of space.
I'm mostly not going to be looking at a 1 pixel wide line at 4k on a 27" monitor. At 32" it might be debatable. Above that you're stacking them oddly (top+bottom, one vertical, or both), or you're down to one monitor and the real estate issue becomes a more pressing issue.
I'm at 'stacking weirdly' and my old main monitor (a "4k" monitor that is actually 3840x2160) is vertical, and angled on the corner of my desk. OS X defaults it to 1080p, which is too big a font for how close I sit to it. Full resolution is way too tiny. So I use 1440 (1.5).
The smallest graphics I use are in grafana, and those happen to be on my vertical monitor. I don't see any weird moire patterns when I scroll them, so if there's an issue with line width, it's well covered by things like not using #00 or #ff for all RGB color channels, which tend to show artifacts more overtly.
But then again, it's not just the hardware it's also the software, and Linux has struggled to keep up with Windows and OS X on some issues related to graphics. The saga of good fonts in X took an unseemly amount of time to sort out.