WHERE: I'm Australian, moved to LA when I was 18 and lived there for 15 years. Then, I moved from Los Angeles to Germany (Duesseldorf), and then to Vienna, Austria.
WHAT SACRIFICE: No more In 'n Out Burger, no more decent Mexican/TexMex food, no more LA food trucks. These are literally the only things I miss about the USA. Literally every other aspect of life has improved massively by leaving the USA - healthcare, food, social life. For the first 4 years I walked to work, ffs. Now I ride a bicycle in combination with the best public transportation options in the world (Austria, Vienna).
GAINED: I've completely lost the brain-dead nationalist mentality that had infected me in my earlier life, I've gained Immense amounts of respect for humanity, I've learned German, I've experienced professional software and hardware development away from Silicon Valley standard practices, and I get to see the USA from outside the decadent, rose-colored bubble from which it is usually experienced. I honestly wish I'd left sooner - every time I go back I'm reminded just how much of a shithole the USA really is ..
Plus, living and loving in Europe is just great. There is no greater joy than a trip through the Balkans for a week adventure, or maybe a jaunt to Spain or southern France. Just being able to travel an hour in any direction and being immersed in absolutely foreign culture is a joy like no other. Definitely a great way to ground oneself.
EDIT: The weather was pretty good in LA. But, still: Americans.