I'd speculate that power sources used by such civilizations would be so exotic to us, we would need new physics to fully describe them.
Also consider that the electromagnetic force is on the order of 10^36 times stronger than gravity. The electromagnetic force is what keeps your butt from falling through your chair, and gives all materials their macroscopic and chemical properties. And it sort of sets a soft limit on the sizes of rigid structures, animals, etc. Note that there are on the order of 10^30 atoms in a blue whale or Sequoia tree, and ~10^33 in a cargo ship.