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228 points curmudgeon22 | 1 comments | | HN request time: 0.346s | source
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rubyn00bie ◴[] No.26612442[source]
This is not surprising to anyone who has ever walked into a GNC, or other health food store... is it even news? They’ve been selling shit like “redline” for many years to do exactly this.

Power fat burner: caffeine + blood thinner. That’s most of what things like redline do. Is it going to work if you don’t exercise? Nope, but it sure as hell does help if you are exercising.

I’d really only recommend it to people focused on losing a lot of weight. If you’re trying to lose 10lbs it’ll never make a difference. If you’re trying to lose 100lbs though, then yeah, 6-12 months worth of slightly increased metabolic rate will probs have a net positive affect.

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1. retrac ◴[] No.26613029[source]
Amphetamine and methamphetamine are actually approved as treatments for morbid obesity by the FDA in America. AMP is actually still used in some cases today, though much more sparingly than historically. The side-effects and potential dependency make their use often very problematic. Still, between increasing the base metabolic rate and energy levels, and suppressing appetite, they do work.

While caffeine has a very different mechanism of action, it does appear to indirectly work on the same dopamine-adenosine system. So it's not too surprising it'd work much the same way for weight loss. And fortunately caffeine seems to be mostly self-limiting in its compulsiveness.