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228 points curmudgeon22 | 1 comments | | HN request time: 0.218s | source
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PragmaticPulp ◴[] No.26612365[source]
> Subjects ingested 3 mg/kg of caffeine or a placebo at 8am and 5pm

3mg/kg is over 250mg of caffeine for an average weight man. Twice a day makes that 500mg.

An 8.4oz can of Red Bull contains 80mg of caffeine. They were giving these people an amount of caffeine equivalent to 6 cans of Red Bull. Not a perfect comparison because Red Bull contains other ingredients, but that's still a lot of caffeine. For another point of reference, that's 2.5 shots of 5 hour energy (200mg caffeine per bottle).

To top it off, the subjects were caffeine-naive, so they had no caffeine tolerance. They must have been feeling extremely energetic.

No wonder they burned more fat. I'm not sure this is going to translate to your casual coffee drinker or someone with a high caffeine tolerance.

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1. carbocation ◴[] No.26612587[source]
Extrapolating from your comment, I guess we'd kind of want a blocked design that is placebo-vs-caffeine and exercise-vs-none.

That would tell us whether there is just an additive effect of high-dose caffeine and exercise, or if somehow the caffeine is interactive with exercise (i.e., has a bigger effect in the exercise group than in the rest group).