However you cannot make useful digital circuits. For digital circuits, the best that you can do is to be content to only design them and buy an FPGA for implementing them, instead of attempting to manufacture a custom IC.
With the kind of digital circuits that you could make in a garage, the most complex thing that you could do would be something like a very big table or wall digital clock, made not with a single IC like today, but with a few dozen ICs.
Anything more complex than that would need far too many ICs.
You can do lithography small but slow and expensive. But small means you need a stack, which is even more expensive. At small sizes, defectivity/variation are really difficult.
So if you want a paradigmatic shift, you need low cost patterning, and the best way I can see is to use clever chemistry and a much different design style.
Then, of course, if by "useful" you mean "commercially viable", it is indeed not going to be competitive against either TSMC or your local 500nm foundry ever.
> So if you want a paradigmatic shift, you need low cost patterning, and the best way I can see is to use clever chemistry and a much different design style.
Is that a speculation, or do you have a more concrete idea about what needs improvement and how? I'm especially curious about the 'much different design style' part. Could you elaborate that?
I call such a CPU as not useful.
It can be a very useful experience to design such a CPU, but you can simulate the design in a logic simulator and you gain nothing by building it.
As a valuable computer building experience, it is more useful to use much older components than digital integrated circuits, where you can see nothing without special instruments, e.g. you can build interesting computer blocks, like adders, registers, counters etc., made with electromechanical relays or with neon glow lamps, where you can see with your eyes how they function.