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249 points randycupertino | 2 comments | | HN request time: 0s | source
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stego-tech ◴[] No.45949690[source]
I feel kinda bad for the writer, because it's a good question: no, curing patients is not a good business model, just like public transit is not a good business model.

What a lot of folks neglect are N+1-order effects, because those are harder to quantify and fail to reach the predetermined decision some executive or board or shareholder has already made. Is curing patients a bad business model? Sure, for the biotech company it is, but those cured patients are far more likely to go on living longer, healthier lives, and in turn contribute additional value to society - which will impact others in ways that may also create additional value. That doesn't even get into the jobs and value created through the R&D process, testing, manufacturing, logistics of delivery, ongoing monitoring, etc. As long as the value created is more than the cost of the treatment, then it's a net-gain for the economy even if it's a net loss for that singular business.

If all you're judging is the first-order impacts on a single business, you're missing the forest for the trees.

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anonymouskimmer ◴[] No.45949762[source]
If a person dies from a disorder in their 20s, they'll never buy your heart medication in their 70s. Today's patient is tomorrow's patient.
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com2kid ◴[] No.45950213[source]
The FDA needs to declare death a disease that patentable drugs can be developed against. All of a sudden the flood gates get opened to encouraging drug research on anything that keeps people alive longer.
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sebmellen ◴[] No.45950753[source]
I quite like this concept. Did you come up with it?
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com2kid ◴[] No.45951000{3}[source]
No, it is a common trope in futurism circles.

Because death is not technically a disease, right now if a company came up with a literal immortality pill they wouldn't be able to get it patented or get FDA approval for it.

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philipkglass ◴[] No.45958132{4}[source]
It's a common trope but also wrong.

If you invent a pill that gives old people the mental and physical vigor of 25 year olds, you don't need to patent or trial it as an immortality pill. Just pick one of the many medical conditions associated with advancing age, like osteoporosis or male pattern baldness, and prove that it safely and effectively treats that condition. If the pill cures baldness and also gives patients improved muscle tone and working memory as a side effect, the FDA won't complain about those beneficial side effects.

Once the drug is approved for treating baldness it can be prescribed off-label for other conditions and/or the manufacturer can progressively run trials for treating additional conditions, similar to how GLP-1 drugs originally developed for diabetes treatment have now been tested and approved for treating obesity.

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1. com2kid ◴[] No.45960707{5}[source]
> Just pick one of the many medical conditions associated with advancing age, like osteoporosis or male pattern baldness,

A drug that maintained telomere length doesn't treat anything directly.

A drug that slows down metabolism and extends life by 20% on average, not patentable.

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2. anonymouskimmer ◴[] No.45960903[source]
Why can't you patent a drug that maintains teleomere length? Or one that slows down metabolism? The FDA does not control the patent office, merely what drugs can be sold in the US. And neither of these inventions seem like they would fall under the limited patentability exclusions.

So invent it here, patent it everywhere, and sell it in the countries that allow it to be sold.