Back in the day (10-12 years ago) at a telecom/cable we accomplished this with F5 Big IP GSLB DNS (and later migrated to A10's GSLB equivalent devices) as the auth DNS server for services/zones that required or were suitable for HA. (I can't totally remember but I'm guessing we must have had a pretty low TTL for this).
Had no idea that Route 53 had this sort of functionality
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