Having grown up in that area of the Midwest, I largely agree with the author's categorization, except that "people on their way to somewhere better who got tired and decided this was good enough" describes a LOT of the midwest, not just Indiana. Significant chunks of Michigan, Ohio, and Missouri, most of Iowa/Kansas/Nebraska, etc.
If you read the history of westward expansion, "got tired and decided this was good enough" is literally true for how much of the area got initially settled (by white people)
Carbondale is slightly better, but I think it’s a notorious party school for very good reasons. Small town Midwest has a saying that “there’s nothing to do here except drink, fuck, and knock over mailboxes”. Most Iowa this is especially true, but Carbondale also gave me that vibe. Also that’s a fucking long drive. St Louis too. Nobody appreciates that Illinois is half as tall as California (not that anyone appreciates how long a trip up and down CA is either).