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111 points pseudolus | 1 comments | | HN request time: 0.207s | source
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pedalpete ◴[] No.45307457[source]
There is a growing body of research showing that increasing slow-wave activity during sleep can improve outcomes, including sleep quality[1], memory, and correlations with amyloid response[2].

Sadly, our latest grant application did not receive funding, but we are supporting other clinical researchers with our technology. Our technology is based on more than a decade of research with 50+ published, peer reviewed studies.

We focus on sleep directly rather than the disease, which means people do not have to wait years for regulatory approvals before they can feel day-to-day benefits.

For those curious about learning more, our approach and links to additional research are on our website https://affectablesleep.com .

Mild-to-moderate Alzheimer’s changes in sleep https://doi.org/10.1016/j.jagp.2024.07.002

Slow-wave activity, memory, and amyloid response https://doi.org/10.1093/ageing/afad228

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arunabha ◴[] No.45311227[source]
Getting better sleep has been a bit of a personal quest for me. Having said that, much as I would love to get the device, having been bitten by a bunch of subscription locked devices by startups, I have (reluctantly) settled on a policy of not purchasing hardware that can't work independently of the company.

Startups are hard at the best of times, hardware startups are harder. When the company making the hardware inevitably goes under, you are left with a useless piece of plastic that you paid a ton of money upfront for, and then paid a hefty sum every month on top.

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pedalpete ◴[] No.45311432[source]
Thanks for this thoughtful response.

The reason we use a subscription is to keep the upfront cost much lower. It's important to us that we make better sleep as accessible as possible. A one-time payment makes that more challenging at this stage.

We also wanted to keep things simple at checkout. Too many options can be confusing, and at this early stage our priority is making it straightforward for people who want to try the technology.

It's a delicate balance.

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1. quesera ◴[] No.45313549[source]
> The reason we use a subscription is to keep the upfront cost much lower. It's important to us that we make better sleep as accessible as possible. A one-time payment makes that more challenging at this stage.

Ugh. Just say "recurring revenue". We're not naive.