Three-Minute Take-Home Test May Identify Symptoms Linked to Alzheimer's Disease

There is a growing body of research showing that increasing slow-wave activity during sleep can improve outcomes, including sleep quality[1], memory, and correlations with amyloid response[2].

Sadly, our latest grant application did not receive funding, but we are supporting other clinical researchers with our technology. Our technology is based on more than a decade of research with 50+ published, peer reviewed studies.

We focus on sleep directly rather than the disease, which means people do not have to wait years for regulatory approvals before they can feel day-to-day benefits.

For those curious about learning more, our approach and links to additional research are on our website https://affectablesleep.com .

Mild-to-moderate Alzheimer’s changes in sleep https://doi.org/10.1016/j.jagp.2024.07.002

Slow-wave activity, memory, and amyloid response https://doi.org/10.1093/ageing/afad228

yes, poor sleep quality leads to bad days, bad days lead to more bad sleep, it is a downward spiral and may impact many of us in our prime years, too.

All the best on your research and funding. Quality sleep has been undervalued, especially among work cultures that value overachieving at the expense of personal health.

Thanks. A researcher we work with has postulated that build-up of metabolic waste (amyloid and tau, among others) directly impairs the glymphatic system, leading to more build-up. A viscous cycle.

I don't think she's the first to postulate this, but I believe she is researching this relationship now.

Though work culture is an important one, we're somewhat more focused on the less self-imposed sleep challenges related to maternity and perimenopause/menopause.

that's a cute Freudian slip (or deliberate joke) - viscous cycle - sure, amyloid and tau are probably very viscous when you poke at them with the laboratory utensil of your choice. And accumulation of them is like a viscious cycle of plaque accumulation and even worse clearance. It seems exponetial