It should be a goal for Earth to send a probe to one of those stars. As the probe will be unmaned, a mission taking a hundred years or more is not out of question.
some combination of nuclear radiation and/or solar seems like it would fit the bill? 100 years is within the useful range of a large radioisotope generator.
https://en.m.wikipedia.org/wiki/Radioisotope_thermoelectric_...
RTGs lose power rapidly as the isotopes decay, and any sort of communication over those distances requires massive power. The Voyagers are essentially dead due to this issue, and they haven’t been out there nearly that long.