The use of Prussian blue is rampant in most painting programs. The reason is that you are essentially getting two paints for the price of one. When applied thinly, it is light and saturated. When applied thickly it is almost black. Contrast that with cobalt blue, which looks the same pretty much however you apply it.
Alizarin crimson behaves similarly.
Painting with either of these pigments it is relatively easy to get superficially impressive effects.
As a painter and also a digital artist, I am always amazed by such physical dimensions of oil paint. Another example is the huge difference between zinc white (low in coverage, good for transparency, slightly cold), and titanium white (high in coverage, good with mixing with other pigments, more neutral).