Genetics required. Natural evolution has zero interest in old people, so there has been no evolutionary pressure to extend lifespan. Possibly even the opposite.
We could apply that pressure, either through selective breeding over generations, or through direct genetic modification. Maybe we aren't quite there yet, but it won't be long.
Experiments on insects with selective breeding have easily tripled lifespans. How well that would transfer to mammals is hard to say, but a substantial increase is certainly possible.
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