There is no physical/chemical/biological reason you can’t live indefinitely with the health and vitality of a 25-35 year old. Aging isn’t a law of nature.
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If not, the point in doing that is the enormous amount of suffering you create while thrashing against an inevitability.
That is not to say you should take naps and wait patiently for death, but it's a line to walk.
This is absurd. Of course mortality is inevitable -- eternity is a very long time -- but working to increase lifespan, prolong one's youth and vigor, and delay the inevitable doesn't cause an "enormous amount of suffering" (far less than the diseases of aging cause) and it's unfair to characterize it as "thrashing" when it can be approached in ways which are thoughtful and reasonable.
I tried to convey that I'm not saying "this is as good as it gets and it's wrong to try for longer life". Your "thoughtful and reasonable" approach was exactly what I had in mind.
What I say leads to suffering arises from denying that mortality is inevitable and tarring those who say otherwise as defeatists. Death is another part of life, as you acknowledged. It unnerves me to see denying that truth cast as a virtue.