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Pig lung transplanted into a human

(www.sciencealert.com)
123 points signa11 | 4 comments | | HN request time: 0s | source
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Stevvo ◴[] No.45077452[source]
I was thinking, big deal, didn't they do a pig heart transplant back in 1999? Turns out that was a popular children's novel and TV series in the UK called "Pig Heart Boy", not reality. First actually pig heart transplant was in 2022.
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echelon ◴[] No.45078708[source]
> First actually pig heart transplant was in 2022.

That patient died shortly thereafter. The condition is critical and there's a lot of immunological pressure put on the patient.

China is smart to study this in living cadavers first. It's much easier to find patients that aren't already on death's door, and there is no need to keep the patient alive. You can run experiment after experiment.

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exhilaration ◴[] No.45079286[source]
I'm almost afraid to ask, what are living cadavers?
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Nextgrid ◴[] No.45079323[source]
Presumably people who are on the verge of death and beyond any kind of proven treatments. They're technically alive but have a very short predicted lifespan.

You can try a novel treatment on those but at the same time are limited by ethical concerns regarding pain and future survival (if the transplant "works", you are now in a tricky situation, as you can't easily do anything that has the potential to make the situation worse... and given it's uncharted territory, anything has the potential to make it worse).

Brain-dead people don't have such limitations. You don't have to worry about causing pain nor shortening potential survival, so you can try things that are likely to "kill" them (cause the transplant to fail, or other issues) and learn from the outcomes.

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nkrisc ◴[] No.45079491[source]
> Brain-dead people don't have such limitations. You don't have to worry about causing pain

Fortunately determining brain death is a problem with a clear-cut answer with a clear line dividing “brain death” and “not brain death”. Right?

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1. moi2388 ◴[] No.45081081{3}[source]
No, but you can measure pain response, and predict pretty well if they ever wake up, so well enough for this.
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2. nkrisc ◴[] No.45082294[source]
Actually it’s less the science of it that concerns me, but whether procedures will be rigorously followed.
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3. actionfromafar ◴[] No.45082300[source]
And in China they can just decide they will never wake up regardless.
4. baranul ◴[] No.45082946[source]
Agree with you on that. People can say that there is a procedure, but verifying that they are following it is another matter. Also curious as to the process for volunteering people for such experiments. Like if there is some paperwork that the family signs off on.