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Pig lung transplanted into a human

(www.sciencealert.com)
123 points signa11 | 5 comments | 27 Aug 25 11:00 UTC | HN request time: 0s | source
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FirmwareBurner ◴[30 Aug 25 16:39 UTC] No.45075966[source]▶
TL;DR: NO, you won't be getting a pig lung anytime soon.

>However, by 24 hours after the transplant had taken place, severe swelling (edema) was observed, possibly as a result of blood flow being restored to the area of the transplant.

Antibody-mediated rejection damaged the tissue further on days three and six of the experiment.

The result of the damage was primary graft dysfunction, a type of severe lung injury occurring within 72 hours of a transplant, and the leading cause of death in lung transplant patients.

Some recovery was taking place by day nine, but the experiment had run its course.

replies(2): >>45076669 #>>45079422 #
1. piombisallow ◴[30 Aug 25 17:54 UTC] No.45076669[source]▶
First heart transplant lived for 18 days post-op, it has to start somewhere.
replies(1): >>45077628 #
2. hallole ◴[30 Aug 25 20:11 UTC] No.45077628[source]▶
That alone is insane, incredible. Hardly measures up to the ideal of leaving the hospital, good as new, but putting that aside: 18 days on a transplant, trans-species organ? I'm in awe!
replies(2): >>45078213 #>>45078623 #
3. ◴[30 Aug 25 21:38 UTC] No.45078213[source]▶
4. wfleming ◴[30 Aug 25 22:43 UTC] No.45078623[source]▶
18 days is how long the first human-to-human heart transplant recipient lived post-op. The more recent first pig heart recipient made it two months.
replies(1): >>45079097 #
5. lokar ◴[30 Aug 25 23:59 UTC] No.45079097{3}[source]▶
And keep in mind people who get these organs are very very ill