My wife went through semi-expetimental therapy (at that time) for her MS. It was tough but ultimately a net benefit.
It all depends on what is at stake - I would consider Ozempic for some weight loss but prefer, for now, go for no sugar and moderate portions. This is not life changing for me so I indeed prefer people who will benefit way more from it to go first.
Brain surgery isn't exactly an industry where "move fast and break things" is an acceptable approach - especially when you are the patient. Considering Neuralink's historical record, going first sounds like a horrible idea to me.
The 20 years of US adventures in Iraq & Afghanistan led to many traumatic brain injury cases analyzed by modern medicine, and the chronic symptoms are worse than one might think.