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331 points breve | 1 comments | | HN request time: 0.214s | source
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inka ◴[] No.45027937[source]
And the part where he says people with this mutation are more prone to bacterial infections is not worrying, because…? In a world of more and more antibiotic resistant bacteria, that does not seem like a good trade-off…
replies(3): >>45028775 #>>45029550 #>>45035716 #
1. lotharcable ◴[] No.45029550[source]
One of the effects of ISG15 deficiency is a disease called "Type I interferonopathy".

Among the symptoms of this disease includes things like necrotic lesions and severe multi-systemic damages.

From what I gather the fact that these people are not more susceptible to viral infections was a surprise. Which probably relates to why the doctors in the parent article were investigating its possible anti-viral properties.