No, it's really the same thing with just different (and more structured) prefix lengths. In IPv4 you usually block a single /32 address first, then a /24 block, etc. In IPv6 you start with a single /128 address, a single LAN is /64, an entire site is usually /56 (residential) or /48 (company), etc.
A /64 is the smallest network on which you can run SLAAC, so almost all VLANs should use this. /56 and /48 for end users is what RIRs are recommending, in reality the prefixes are longer, because ISPs and hosting providers wants you to pay like IPv6 space is some scarse resource.
Note that for the sake of blocking internet clients, there's no point blocking a /128. Just start at /64. Blocking a /128 is basically useless because of SLAAC.