Perhaps it is worth noting that all super computers I know (like the Dutch Snellius and the Finnish Lumi) are Slurm clusters with login nodes.
Bioinformaticians (among others) in (for example) University Medical Centers won’t get much more bang for the buck than on a well managed Slurm cluster (ie with GPU and Fat nodes etc to distinguish between compute loads). You buy the machines, they are utilized close to 100% over their life time.
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