Really love the ideas behind Deno, and tried to do things the Deno way (Deno.json, JSR, modern imports, Deno Deploy) for a monorepo project with Next.js, Hono and private packages. Some things like Hono worked super well, but Next.js did not. Other things like types would sometimes break in subtle ways. The choice of deployment destination e.g. Vercel for Next also gave me issues.
Here is an example of a small microcut I faced (which might be fixed now) https://github.com/honojs/hono/issues/1216
In contrast, Bun had less cognitive overhead and just "worked" even though it didn't feel as clean as Deno. Some things aren't perfect with Bun either like the lack of a Bun runtime on Vercel
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