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What I learned gathering nootropic ratings (2022)

(troof.blog)
126 points julianh65 | 2 comments | 02 Jul 25 13:29 UTC | HN request time: 0.611s | source
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cckolon ◴[02 Jul 25 14:59 UTC] No.44444571[source]▶
> 5 - 9 means strong effects, definitely not placebo.

It’s impossible for anyone to say this convincingly about their own experience. If it were easy to tell whether an effect was due to placebo, we wouldn’t need blinded trials!

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1. elbasti ◴[02 Jul 25 15:37 UTC] No.44445036[source]▶
Actually, a lof of blind trials are hard to run precisely because it's so obvious if you're not on the placebo side.

Like...nobody could ever take a macro dose of LSD or mushrooms and not know it.

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2. foolswisdom ◴[02 Jul 25 15:44 UTC] No.44445126[source]▶
That's because it's obvious due to effects other than the one you're trying to observe. Which is of course the case when you're dealing with psychedelics (and of course many other drugs).