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262 points Anon84 | 1 comments | | HN request time: 0.198s | source
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suzzer99 ◴[] No.44408657[source]
I've lost one of my best friends to what I think is schizophrenia. We don't know because she's cut off all contact with friends and family and refuses to see a doctor. It's definitely psychosis. She thinks she's in some kind of Truman show that she calls "the game". Since none of her friends or family are willing to admit to it, then we must be in on it.

We don't know her full family medical history because her dad was adopted. I do know that she was "microdosing" and macro-dosing hallucinogens for years. Mostly acid and shrooms as far as I know. She followed the band Phish around with a group of friends. I can't imagine most of those shows were sober.

We've also seen a few incidents of paranoia when she was under the influence of drugs/alcohol going back decades. So it feels like this was always there in some form, but maybe the estrogen was holding it back before menopause hit. I read an article about women who get schizophrenia after menopause that suggested this could be the case.

Anyway, whenever I see wellness healers and the like extolling the virtues of psilocybin, I want to point out that there could be a downside. We don't know that all of her hallucinogen use over the years contributed to this. But it's certainly a possibility.

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winrid ◴[] No.44408738[source]
If you have a genetic predisposition to schizophrenia it's starting to seem like drugs that seem harmless like marijuana (specifically THC?) can definitely bring it out. At least, that's what seemed to happen to my mother and another friend.
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quickthrowman ◴[] No.44413494[source]
Or perhaps people predisposed to schizophrenia are more likely to seek out drugs. Something like 9 in 10 schizophrenics smoke cigarettes too, is schizophrenia caused by nicotine or do schizophrenics smoke because they’re predisposed to do so? I find it hard to believe that so many schizophrenics smoke cigarettes and are not also predisposed towards using other drugs.

I think blindly accepting the statement ‘drugs can cause schizophrenia’ is harmful because we don’t actually know if the drugs trigger it or if the disorder makes them seek out drugs.

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1. LoganDark ◴[] No.44423786[source]
Some drugs have been known to activate schizophrenia; particularly psychedelics like LSD. However, in order for this to happen, one likely already needs to have a genetic predisposition. I use LSD about once every week or two and I haven't noticed any schizophrenia yet, so it is very much a YMMV.