I'm currently developing a middleware that connects Nvidia PhysX to GameMaker. There's still a lot of work left but I have most features working in some capacity. Dynamic and static actors, primitive/convex/triangulated shapes, joints, character controllers, GPU accelerated PBD particles and deformables, etc.
GameMaker is primarily a 2D engine and offers limited options for 3D, but it is possible if you know how to use vertex buffers. I'll probably post it here once it's a little farther along, but I'm pretty proud of my progress so far. I'm hoping I can use it to support myself in some way, but there's a lot of anxiety in selling a niche project like this.