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262 points Anon84 | 1 comments | | HN request time: 0.832s | source
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Throwaway42754 ◴[] No.44408788[source]
I have schizoaffective disorder, induced by a bad trip from marijuana. It was like the 3rd time I had tried weed, and I naively took too much.

For me psychosis feels like pattern matching going on extreme overdrive, while at the same time memory goes to shit. It's truly an awful illness, and what's worse is that the current medical treatments are bad. I've been fortunate enough where I can get by on a low dose olanzapine, but for many people they simply don't work at all.

Even though I'm doing well enough to function normally and hold down a good, well paying job, it's impossible to find a partner. If I were to have kids, I would have to go through one of the embryo prescreening services. I am strongly in support of these screening services - the disease is truly horrible.

There has been little progress on treatments for schizophrenia, the mechanism of action of these drugs has remained the same for decades. The side effects are almost as bad as the disease, which is why so many schizophrenic stop taking them. The only novel medication recently released is Cobenfy, which I have not tried yet.

Personally I am holding out hope that schizophrenia has some basis as an autoimmune disease. There was a cancer patient who had a bone marrow transplant and ended up being cured: https://www.nytimes.com/2018/09/29/opinion/sunday/schizophre...

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ChrisMarshallNY ◴[] No.44408844[source]
I have family with that.

The most striking thing, is the absolute certainty of the thinking. They feel as if their thinking is crystal-clear, and that they are the only one that "sees the patterns."

Currently, they're doing well. I know of others, that are not so fortunate.

It seems that pot is about the worst thing that a schizoaffective/schizophrenic person can use. They are better off chewing tabs of acid. I've not used it in about 45 years, and I've heard that today's pot is a heck of a lot stronger than what I remember.

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mandmandam ◴[] No.44409442[source]
> It seems that pot is about the worst thing that a schizoaffective/schizophrenic person can use.

This isn't entirely true, and it's a dangerous misconception. High THC, low CBD cannabis wouldn't be recommended, but that's exactly what making cannabis illegal selects for.

High CBD, low/zero THC cannabis, on the other hand, will probably be one of the paths to treatment if we ever get over our Reefer Madness and pharmaceutical obsession.

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talentedcoin ◴[] No.44410192[source]
“Dangerous misconception”? Get out of here with that. Cannabis is dangerous for schizoaffective people. Why are people that smoke pot so tiresome about this? Just accept that it’s not good for everyone!
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1. mandmandam ◴[] No.44411580[source]
> “Dangerous misconception”? Get out of here with that.

I will not.

The demonization of cannabis has led directly to it becoming high THC and low CBD, as I said. It also has lead to it often being tainted with all manner of adulterants, from ketamine to glass beads to plaster dust to worse.

> Cannabis is dangerous for schizoaffective people.

CBD is a leading target of research for it's anti-psychotic properties; and if you don't know this it's a complete mystery to me why you feel entitled to weigh in.

And it's not even the only compound in cannabis that is being investigated; there are others with anti-psychotic and synergistic potential.

> Why are people that smoke pot so tiresome about this?

What if what I'm saying might be true, and you're dead wrong to accuse anyone who disagrees of being a 'tiresome stoner'?

... Because, in fact, it may well be [0].

> Just accept that it’s not good for everyone!

If it's not for you, that's fine; but the wilful ignorance around cannabis over decades has caused far, far more harm than cannabis ever has.

Can you accept that it will may well have a role in treating "psychosis, in general and schizophrenia, in particular" [0]?

0 - https://pubmed.ncbi.nlm.nih.gov/22716160/

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